SJK Foundation (Ireland), CupFoundJo (the UK) and Missie Tumor Onbekend (the Netherlands), three national patient organisations dedicated to improving quality of care & life and providing information and support for patients with cancer of unknown primary (“CUP”) have joined forces and are launching the first pan-European and world awareness week for CUP in 2021. It is our goal to increase much needed awareness and a sense of urgency for CUP as a very challenging oncological syndrome that needs more support from global communities, research institutions and medical organisations to achieve better care opportunities.   We believe we need to really raise alarm bells on enhancing access to better molecular diagnostics/personalised diagnostics/CGP and targeted treatment/trials for all cancer patients. We want to use the growing awareness for CUP to further educate patients, medical specialists and policy makers on this important matter and show parties what diagnostics/care is being developed and will soon be available for patients. We hope that this website will help all those with an interest in cancer of unknown primary to connect and contribute to potential research collaborations across the world.