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CUP diagnostics

AI

  1. AI-based pathology predicts origins for cancers of unknown primary | Nature
  2. A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns

Biomarker testing

  1. Cancer Medicine – 2024 – Harvey – Biomarkers of systemic inflammation provide additional prognostic stratification in cancers of unknown primary

Genomic profiling

  1. Development and Validation of a Novel Nomogram for Individualized Prediction of Survival in Cancer of Unknown Primary
  2. Feasibility and value of genomic profiling in cancer of unknown primary: real-world evidence from prospective profiling study

Next Generation Sequencing

  1. A Challenging Task_ Identifying Patients with Cancer of Unknown Primary (CUP) According to ESMO Guid
  2. CUP-ONE-esmo-abs
  3. Mileshkin_CUPISCO primary_ESMO 2023
  4. Targeted Next-Generation Sequencing for the Management of Patients Diagnosed With a Cancer of Unknow

Whole Genome Sequencing

  1. Complete genomic characterization in patients with cancer of unknown primary origin in routine diagnostics
  2. Comprehensive genomic and epigenomic analysis in cancer of unknown primary guides molecularly-inform

Other

  1. Carcinoma of unknown primary (CUP): an update for histopathologists

CUP epidemiology

British Journal of Cancer

  1. Intrahepatic cholangiocarcinoma hidden within cancer of unknown primary

An audit of CUP

  1. An audit of cancer of unknown primary notifications A cautionary tale for population health research using cancer registry data

CUP guidelines

ESMO

  1. Cancer of unknown primary: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up5

CACA guideline for diagnosis

  1.  China Anti-Cancer Association guideline for diagnosis and treatment of cancer of multiple and unknown primaries (2024 edition) 

CUP treatments

Archive

  1. New rising entities in cancer of unknown primary: Is there a real therapeutic benefit?
  2. Nivolumab and ipilimumab in recurrent or refractory cancer of unknown primary: a phase II trial
  3. Characterisation and outcomes of patients referred to a regional cancer of unknown primary team
  4. Efficacy of pembrolizumab in patients with advanced cancer of unknown primary (CUP): a phase 2 non-randomized clinical trial
  5. Immune and genomic biomarkers of immunotherapy response in cancer of unknown primary
  6. Progress in refining the clinical management of cancer of unknown primary in the molecular era

2024-Kramer-Lancet

  1.  Molecularly guided therapy versus chemotherapy after disease control in unfavourable cancer of unknown primary (CUPISCO): an open-label, randomised, phase 2 study 

Supportive care & Quality of life

Archive

  1. Rare cancers and cancer of unknown primary: Here’s what you should know!
  2. A qualitative study of patients with Cancer of Unknown Primary: Perceptions of communication, understanding of diagnosis and genomic testing, and information needs

Nationwide survey on family

  1. Nationwide survey on family caregiver‑perceived experiences of patients with cancer of unknown primary site

Jpn. J. Clin. Oncol

  1. Psychological burden on patients with cancer of unknown primary: from onset of symptoms to initial treatment

Other

Archive

  1. Healthcare Costs Before and After Diagnosis of Cancer of Unknown Primary Versus Ovarian Cancer in Australia
  2. How can we deliver on the promise of precision medicine in oncology and beyond? A practical roadmap for action
  3.  Modified study designs to expand treatment options in personalised oncology: a multistakeholder view
  4. Stakeholders’ expectations of precision medicine: A qualitative study to identify areas of (mis) alignment
  5. Systematic review of the CUP trials characteristics and perspectives for next-generation studies
  6. CUP Research Jos Friends

CUP JOURNEY

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CUPFOUNDJO

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jo's friends foundation

CUPP-NL

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cupp-nl

CUPISCO TRIAL

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ROCHE

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NATURE COMMU.

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research worldwide programs
research worldwide programs

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